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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS1
All Species:
14.24
Human Site:
Y538
Identified Species:
31.33
UniProt:
O75925
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75925
NP_057250.1
651
71836
Y538
F
H
M
T
P
M
P
Y
D
L
Q
G
L
D
F
Chimpanzee
Pan troglodytes
XP_523109
766
83908
Y653
F
H
M
T
P
M
P
Y
D
L
Q
G
L
D
F
Rhesus Macaque
Macaca mulatta
XP_001082800
642
70843
D530
H
M
T
P
M
P
Y
D
L
Q
G
L
D
F
F
Dog
Lupus familis
XP_535524
651
71773
Y538
F
H
M
T
P
M
P
Y
D
L
Q
G
L
D
F
Cat
Felis silvestris
Mouse
Mus musculus
O88907
651
71599
Y538
F
H
M
T
P
M
P
Y
D
L
Q
G
L
D
F
Rat
Rattus norvegicus
O70260
628
68345
Y516
S
S
L
P
L
H
E
Y
P
P
A
F
P
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516107
756
82793
P637
R
H
P
F
H
M
T
P
M
S
Y
D
L
Q
G
Chicken
Gallus gallus
NP_001026627
564
62782
K452
S
S
H
Q
Q
S
N
K
N
K
K
V
E
V
I
Frog
Xenopus laevis
NP_001079161
649
71676
P537
P
F
H
M
A
H
M
P
Y
D
L
Q
G
L
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
M631
A
A
S
A
N
L
P
M
R
Q
M
S
Q
Q
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
F566
D
A
I
G
T
F
D
F
V
A
N
G
M
E
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.9
98.6
99.6
N.A.
98
58.6
N.A.
82.2
82.9
87
N.A.
N.A.
N.A.
N.A.
24
N.A.
Protein Similarity:
100
84.9
98.6
99.8
N.A.
98.7
72
N.A.
84.2
85
94.3
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
100
6.6
N.A.
20
0
0
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
100
13.3
N.A.
20
13.3
0
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
19
0
10
10
0
0
0
0
10
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
10
10
37
10
0
10
10
37
10
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
0
0
10
10
0
% E
% Phe:
37
10
0
10
0
10
0
10
0
0
0
10
0
10
46
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
10
46
10
0
19
% G
% His:
10
46
19
0
10
19
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
10
0
10
10
0
0
0
0
% K
% Leu:
0
0
10
0
10
10
0
0
10
37
10
10
46
19
10
% L
% Met:
0
10
37
10
10
46
10
10
10
0
10
0
10
0
0
% M
% Asn:
0
0
0
0
10
0
10
0
10
0
10
0
0
0
10
% N
% Pro:
10
0
10
19
37
10
46
19
10
10
0
0
10
0
0
% P
% Gln:
0
0
0
10
10
0
0
0
0
19
37
10
10
19
0
% Q
% Arg:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
19
19
10
0
0
10
0
0
0
10
0
10
0
0
0
% S
% Thr:
0
0
10
37
10
0
10
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
46
10
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _